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Lei Sun Selected Research

Carcinogenesis

3/2024Selective degradation of PL2L60 by metabolic stresses‑induced autophagy suppresses multi‑cancer growth.
2/2024Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3KBTBD2.
12/2023Tumor associated neutrophils governs tumor progression through an IL-10/STAT3/PD-L1 feedback signaling loop in lung cancer.
12/2022Lipidomics and Transcriptomics Differ Liposarcoma Differentiation Characteristics That Can Be Altered by Pentose Phosphate Pathway Intervention.
12/2022RNA and RNA Derivatives: Light and Dark Sides in Cancer Immunotherapy.
1/2022Mammalian eIF4E2-GSK3β maintains basal phosphorylation of p53 to resist senescence under hypoxia.
1/2020miR-552 promotes laryngocarcinoma cells proliferation and metastasis by targeting p53 pathway.
1/2019HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2.
1/2018Renal proteomic analysis of RGC-32 knockout mice reveals the potential mechanism of RGC-32 in regulating cell cycle.
7/2017An unusual intragenic promoter of PIWIL2 contributes to aberrant activation of oncogenic PL2L60.
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Lei Sun Research Topics

Disease

168Neoplasms (Cancer)
05/2024 - 09/2004
60Inflammation (Inflammations)
04/2024 - 07/2002
59Infections
05/2024 - 08/2008
25Neoplasm Metastasis (Metastasis)
03/2024 - 08/2012
23Fibrosis (Cirrhosis)
04/2024 - 03/2011
23Obesity
12/2022 - 10/2009
21Hypoxia (Hypoxemia)
01/2022 - 05/2005
20Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2023 - 01/2014
19Hepatocellular Carcinoma (Hepatoma)
11/2023 - 10/2011
16Insulin Resistance
02/2024 - 10/2013
16Body Weight (Weight, Body)
03/2023 - 12/2008
15Carcinogenesis
03/2024 - 03/2008
15Wounds and Injuries (Trauma)
10/2023 - 12/2006
15Acute Lung Injury
01/2020 - 07/2002
14Lung Neoplasms (Lung Cancer)
04/2024 - 01/2013
14COVID-19
02/2024 - 01/2020
14Virus Diseases (Viral Diseases)
03/2023 - 06/2009
14Schizophrenia (Dementia Praecox)
02/2023 - 05/2014
13Alzheimer Disease (Alzheimer's Disease)
03/2024 - 01/2013
12Adenocarcinoma of Lung
10/2023 - 10/2008
12Atherosclerosis
01/2023 - 04/2015
11Weight Gain
10/2023 - 05/2014
10Non-alcoholic Fatty Liver Disease
12/2023 - 02/2018
10Breast Neoplasms (Breast Cancer)
02/2022 - 02/2010
9Colorectal Neoplasms (Colorectal Cancer)
01/2024 - 01/2017
9Pain (Aches)
01/2024 - 08/2013
9Carcinoma (Carcinomatosis)
12/2023 - 09/2008
9Type 2 Diabetes Mellitus (MODY)
12/2023 - 01/2016
9Mitochondrial Diseases (Mitochondrial Disease)
11/2023 - 05/2014
9Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 10/2012
9Cystic Fibrosis (Mucoviscidosis)
01/2022 - 04/2011
8Lung Injury
03/2024 - 08/2008
8Sepsis (Septicemia)
01/2022 - 07/2004
8Ischemia
01/2019 - 10/2006
7Epilepsy (Aura)
05/2024 - 10/2012
7Liver Neoplasms (Liver Cancer)
01/2024 - 10/2016
7Necrosis
11/2023 - 10/2007
7Thalassemia
11/2023 - 04/2014
7Pulmonary Fibrosis (Fibrosing Alveolitis)
01/2023 - 01/2017
7Leukemia
10/2022 - 04/2002
7Gestational Diabetes (Gestational Diabetes Mellitus)
01/2022 - 11/2011
6Cognitive Dysfunction
04/2024 - 01/2012
6Spinal Cord Injuries (Spinal Cord Injury)
11/2023 - 06/2012
6Hemorrhage
10/2023 - 11/2009
6Pneumonia (Pneumonitis)
01/2023 - 07/2009
6Liver Cirrhosis (Hepatic Cirrhosis)
01/2023 - 01/2020
6Adenocarcinoma
01/2023 - 02/2017
6Lung Diseases (Lung Disease)
04/2022 - 03/2008
6Colonic Neoplasms (Colon Cancer)
01/2022 - 10/2016
6Myocardial Infarction
10/2021 - 01/2011

Drug/Important Bio-Agent (IBA)

77Proteins (Proteins, Gene)FDA Link
04/2024 - 04/2002
37Biomarkers (Surrogate Marker)IBA
04/2024 - 01/2013
35CytokinesIBA
03/2024 - 07/2006
20Messenger RNA (mRNA)IBA
04/2024 - 04/2002
19Antiviral Agents (Antivirals)IBA
02/2024 - 09/2008
19MicroRNAs (MicroRNA)IBA
12/2023 - 10/2009
17RNA (Ribonucleic Acid)IBA
12/2023 - 10/2013
17LipidsIBA
12/2023 - 06/2009
15Peptides (Polypeptides)IBA
10/2022 - 02/2012
14Glucose (Dextrose)FDA LinkGeneric
02/2024 - 02/2010
14Olanzapine (Zyprexa)FDA Link
01/2022 - 05/2014
13InterferonsIBA
12/2023 - 06/2009
133-carboxamido-4-hydroxynaltrexoneIBA
01/2022 - 11/2018
12CollagenIBA
04/2024 - 06/2009
12Interleukin-6 (Interleukin 6)IBA
10/2022 - 09/2009
12Long Noncoding RNAIBA
04/2022 - 01/2016
11Therapeutic UsesIBA
09/2023 - 08/2008
11Reactive Oxygen Species (Oxygen Radicals)IBA
01/2023 - 01/2011
11CateninsIBA
01/2022 - 12/2015
11Acetylcholine (Acetylcholine Chloride)FDA Link
01/2017 - 10/2006
10Indicators and Reagents (Reagents)IBA
01/2023 - 09/2004
10Antipsychotic Agents (Antipsychotics)IBA
01/2022 - 05/2014
9DNA (Deoxyribonucleic Acid)IBA
04/2024 - 04/2002
9Cyclophilin AIBA
03/2024 - 12/2010
9Insulin (Novolin)FDA Link
02/2024 - 10/2013
9Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2024 - 10/2013
9LipopolysaccharidesIBA
11/2023 - 06/2010
8Bleomycin (Blenoxane)FDA LinkGeneric
03/2024 - 03/2005
8Small Interfering RNA (siRNA)IBA
03/2024 - 01/2019
8AntibodiesIBA
02/2024 - 05/2011
8Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2024 - 07/2009
8Phosphotransferases (Kinase)IBA
12/2023 - 10/2007
8LigandsIBA
01/2023 - 10/2010
8Paclitaxel (Taxol)FDA LinkGeneric
06/2022 - 10/2008
7Protein Kinases (Protein Kinase)IBA
03/2024 - 03/2005
7Interleukin-10 (Interleukin 10)IBA
12/2023 - 07/2009
7Triglycerides (Triacylglycerol)IBA
03/2023 - 07/2011
7AntioxidantsIBA
01/2023 - 01/2013
7Narcotic Antagonists (Opioid Antagonists)IBA
01/2022 - 01/2019
6AntigensIBA
04/2024 - 08/2017
6InterleukinsIBA
10/2023 - 06/2016
6CholesterolIBA
01/2023 - 09/2015
6Interleukin-8 (Interleukin 8)IBA
05/2022 - 05/2009
6Oxygen (Dioxygen)IBA
04/2022 - 05/2005

Therapy/Procedure

79Therapeutics
05/2024 - 05/2007
14Drug Therapy (Chemotherapy)
04/2024 - 03/2008
13Immunotherapy
12/2023 - 05/2017
8Precision Medicine
01/2024 - 10/2016
7Transplantation
11/2022 - 12/2008
6Aftercare (After-Treatment)
01/2023 - 04/2013